Combat Rifles and Grenades FTW.
Grenades! Yes! I think it was at level 13 when I found a nade upgrade that made it a sticky that would only detonate when contacting an enemy. So from there on in I've been tossing out a nade between myself and a "big guy" giving him a few crits to the head and laughing when gets all chunky from running into the nade :haha: