Seems to be running fine @ 1440p with my 6800 XT, although it's registering as using 15800(ish) memory. Game defaulted to ultra settings and is pushing 140+ FPS normally but there was one area (spider caverns) where it bogged down significantly. Cut scenes are 30 FPS which I'm assuming is a console limitation?
Interestingly, the game took over the RGB lighting on my Corsair keyboard by turning it all red with only the Q and Spacebar lit up in white (which happen to be the only two keyboard keys I'm using at the moment).
edit: The audio is pretty impressive as well.... fully submersive on my surround speakers, and they actually have a "Quad" option if a person didn't want to fiddle with the settings for 4 speakers in a 5.1 windows configurations.