RGB Fusion.....what a piece of work that is....!
It's behaving for me now in that I just left it at cycling colours. My RAM and fans are in sync consistently now.
What monitor is that?
Does it have an option to lock in a "hardware" profile? That's the ticket if it's available. That way you can set the profile into whatever small programmable chip part of the onboard controller and forget it regardless of what the software says (you'd set the software to not run on startup and only launch it when you want to change the profile).